No WSU OC has had to worry about Vita Vea - or anyone close to his level - since 2017. But honestly, I’m not going to stop running because he’s there…because then they don’t have to defend it.
You run as much variety as you can. You scheme all week to find things that might work, and then You try them until something does. If you don’t find anything, it might mean you’re a bad team. If you can never find anything it might mean you’re a bad coach.
If you’ve got a bad OL, you have to try something else. Misdirection and short, quick passes come to mind - stuff that forces the defense to slow itself down, if your OL can’t. Not a floating pass all the way to the sideline at a stationary receiver 3 yards behind the LOS, and certainly not that throw 15 times per week with a QB who throws at their feet.